Technical Program

Paper Detail

Paper:ITT-P4.11
Session:Biomedical and biometric applications
Time:Friday, May 21, 15:30 - 17:30
Presentation: Poster
Topic: Industry Technology Track: Biomedical
Title: TECHNIQUES FOR DETECTING APPROXIMATE TANDEM REPEATS IN DNA
Authors: Thao Tran; Georgia Institute of Technology 
 Vincent Emanuele II; Georgia Institute of Technology 
 G. Tong Zhou; Georgia Institute of Technology 
Abstract: The detection of tandem repeats is important in biology and medicine as it can be used for phylogenic studies and disease diagnosis. This paper proposes two techniques for detecting approximate tandem repeats (ATRs) in DNA sequences. First, an evolutionary force heuristic is proposed to merge interspersed perfect tandem repeat sequences into an ATR structure. Next, a more general method is presented using a product spectrum of Fourier nucleotide subsequences to detect hidden periodicity. The Fourier method is sensitive to ATRs and is robust in the presence of substitutions, insertions, and deletions.
 
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